Interazione valtrax (isopropamide ioduro + diazepam) e fluvoxamina 100 mg

Buongiorno,
sono in cura con il valtrax e la fluvoxamina 100 mg. Ho potuto constatare su drugs. com come ci sia una forte interazione fra questi due farmaci. In particolar modo viene riportato che:

GENERALLY AVOID: One study has reported that fluvoxamine significantly decreases the clearance of diazepam and desmethyldiazepam in healthy volunteers. The mean half-life of diazepam increased from 51 hours to 118 hours. The mechanism is inhibition of hepatic CYP450 metabolism. Other benzodiazepines that are metabolized by this route may also be affected.

MANAGEMENT: The manufacturer states that fluvoxamine and diazepam should not be given together. Lorazepam, oxazepam, and temazepam are metabolized by glucuronidation and are not expected to be affected by fluvoxamine.

A questo punto volevo chiedervi se possono essere utilizzati entrambi farmaci oppure se tecnicamente non dovrei assumere proprio i due farmaci.
Grazie.
[#1]
Dr. Francesco Saverio Ruggiero Psichiatra, Psicoterapeuta 42.3k 1k 63
In teoria andrebbe prescritta un'altra terapia.

Dr. F. S. Ruggiero

http://www.francescoruggiero.it

https://wa.me/3908251881139
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