Astinenza da cannabis regolarmente prescritta

Salve,
da un anno circa mi è stata prescritto per insorria resistente a farmaci convenzionali,
bedrolite e bedrocan acon alto valore di cbd,
ho smesso per perdita di efficacia,
ma dopo 2 giorni i sintomi di astinenza sono realmente insopportabili,
considerando che già soffro di ansia generalizzata e insonnia.
Le benzodiazepine sono inefficaci perchè bloccate dal thc che rimarrà a lungo nel corpo.
Riporto dati da letteratura scientifica:
CB1 receptors block GABAa- but not GABAb- mediated synaptic responses
The present study demonstrated that WIN 55,212-2 inhibited evoked GABAA receptor-mediated IPSCs in a concentration- dependent manner, without affecting GABAB-mediated IPSCs. The differential modulation of GABAA and GABAB synapses by monoamine receptor agonists has been shown previously in mid- brain dopamine neurons (Johnson et al., 1992; Cameron and Williams, 1993; Shoji et al., 1999). However, it is not clear whether GABAA and GABAB synaptic responses arise from different populations of inhibitory terminals in the hippocampus (Nurse and Lacaille, 1997). Our results support the hypothesis that the innervation of GABAA and GABAB receptors arises from distinct inhibitory terminals and are consistent with the idea that CB1 receptors are found on inhibitory basket cell terminals (Katona et al., 1999) that constitute a major source of GABAA- mediated synaptic input onto CA1 pyramidal neuron somata (Buhl et al., 1995). This differential targeting of inhibitory termi¬nals by CB1 receptors is in contrast to ^,-opioid receptors, which inhibit both GABAA- and GABAB-mediated synaptic transmis- sion in the hippocampus (Lupica et al., 1992).

Sto affrontando il weekend e non so come fare fino a martedi.
Cosa posso fare prima di andare al pronto soccorso?

Grazie